Ammm:Mm aplus

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I. Introduction

One is recommended to read through and understand the background knowledge of polarizable force field AMOEBA, in order to have a better learning experience of the next generation AMOEBA+ force field. As indicated by the name, AMOEBA+ is based on the AMOEBA model with incoporation of essential physical effects that are missing in AMOEBA model. With the short-range charge penetration and charge transfer effects being included, AMOEBA+ potential is able to follow the energy components by the Symmetry Adapted Perturbation Theory (SAPT).

Below brief description of the SAPT theory is introduced, followed by the specific interactions/physical effects that are incoporated in AMOEBA+ potential. In the last part, brief summary of the current status of the parametrization of the AMOEBA+ force field is given.

II. Symmetry Adapted Perturbation Theory

III. New potential energy terms

These energy terms are newly added, which means they are not in the AMOEBA model.

a. Charge penetration

b. Charge flux

c. Charge transfer

IV. Other improvements

a. Polarization

b. Polarizability

c. van der Waals

d. Valence parameters

V. Parametrization